England will be without injured back rowers Courtney Lawes and Nathan Hughes for their final Six Nations game against Ireland and have called up Exeter flanker Don Armand as a result.
Lawes and Hughes will have scans on Monday after picking up knee injuries in the loss to France on Saturday.
Zimbabwe-born Armand, 29, has won one cap, as a replacement against Argentina on the 2017 summer tour.
Saracens duo Nick Isiekwe, 19, and Alex Lozowski are also in a 32-man squad.
Ireland clinched the 2018 Six Nations with a round to spare and will travel to Twickenham on Saturday eyeing only their third Grand Slam.
England squad in full:
Backs: Mike Brown (Harlequins), Danny Care (Harlequins), Elliot Daly (Wasps), Nathan Earle (Saracens), Owen Farrell (Saracens), George Ford (Leicester Tigers), Jonathan Joseph (Bath Rugby), Alex Lozowski (Saracens), Jonny May (Leicester Tigers), Henry Slade (Exeter Chiefs), Marcus Smith (Harlequins)*, Denny Solomona (Sale Sharks), Ben Te'o (Worcester Warriors), Anthony Watson (Bath Rugby), Richard Wigglesworth (Saracens).
Forwards: Don Armand (Exeter Chiefs), Dan Cole (Leicester Tigers), Luke Cowan-Dickie (Exeter Chiefs), Charlie Ewels (Bath Rugby), Jamie George (Saracens), Dylan Hartley (Northampton Saints), James Haskell (Wasps), Alec Hepburn (Exeter Chiefs), Nick Isiekwe (Saracens), Maro Itoje (Saracens), George Kruis (Saracens), Joe Launchbury (Wasps), Joe Marler (Harlequins), Chris Robshaw (Harlequins), Sam Simmonds (Exeter Chiefs), Kyle Sinckler (Harlequins), Mako Vunipola (Saracens).
* Apprentice player
Source: BBC Rugby Union News